Search Results for: Solid Dosage Form

A softgel is an oral medication dose form in the shape of a customized capsule. They are made up of a gelatin-based covering encasing a liquid fill. Softgel envelopes are made of gelatin, water, an opacifier, and a plasticizer like glycerin or sorbitol.   This sort of machine is typically used to fill soft gelatin […]

Aceclofenac is a new type of powerful antipyretic, analgesic and anti-arthritic drug—in order to make aceclofenac into dispersible tablets more efficiently, the preparation process of aceclofenac dispersible tablets was carried out in this paper. Research. Based on the orthogonal test L9(3)4, the dosage of its main functional excipients was selected, and the preparation process of

What is trituration?   Trituration is the name of various different materials processing processes. In some ways, it is a type of milling (reducing the particle size of a substance). In another meaning, it is the process of producing an uniform powdered material by completely combining and crushing constituent ingredients. The trituration method entails pressing

Effervescent tablets are uncoated tablet formulations comprising medicinal agent mixes with acid compounds and carbonates  that quickly react in the water presence to produce CO2. They are solid dosage forms that must be solubilized or mixed in a cup of water before being administered.   Effervescent tablets contain unique properties that enable for the quick

experience, machinery, and excipients used, manufactured or compressed tablets may have problems that are visible immediately or only after storing.   The following are issues related to tablet manufacture and how to solve them. Lamination and capping The detachment or splitting of the top or bottom of a compacted tablet from the main structure of the

The sugar coating method involves repeatedly adding a coating solution or mixture and drying off the solvent to build up layers of coating material on the tablet cores. The procedure is made up of several stages, every of which is intended to perform a certain purpose. A standard sugar-coating technique includes six steps:   The

A variety of issues might arise throughout any coating procedure. Such concerns are frequently related to formulation issues that have been amplified by those associated with processing.   1.Surface cracking of the coatings Tablet cores that expand during or after coating are more prone to break the coating. Such expansion could be caused by stress-relaxation

First of all what is mixing ? A unit process known as mixing occurs when two or more components are handled in a way that each particle or molecule of the components lies as closely as possible in touch with a particle or molecule of the other components. There are several methods which are involved in

Dry granulation, also known as precompression or twofold compression, is a procedure for increasing particle size that is intended to enhance the flow and compression properties of powders that would not otherwise be appropriate for compression. Powder particles are compressed into bulky compacts, which are then broken down into smaller granules to create granules that

Pharmaceutical emulsions are immiscible liquid disperse systems in which the dispersed phase is made of tiny globules of a liquid scattered across a vehicle. The dispersion medium is referred to as the continuous or external phase in emulsion nomenclature, whereas the dispersed phase is the discontinuous or internal phase.   Although it can be as